2015年6月14日星期日

Nephritis, diabetes can not eat drugs

Nephritis, diabetes mellitus, diabetic nephropathy is the starting point for many, the main symptoms of proteinuria, but because of mild symptoms, many patients failed to detect. The current treatment of diabetic nephropathy with drug-based, but the selection of inappropriate drugs is likely to lead to exacerbations. So what diabetes drugs can cause nephritis eat sicker it?
Why medication incorrectly can cause aggravation? This is because the kidney is the main organ of drug metabolism, long-term medication will increase the burden on the kidney, damage the kidneys. Nephritis may lead to exacerbation of drugs:
1. Diuretics: Diuretics are one of the medicines cause disease exacerbations. Diuretics fewer side effects, but using too much will also cause problems. Diuretics are our nephrology one of the most widely used drugs, but the use of excessive doses, long or use the wrong time can cause kidney damage, or to increase the time the original kidney disease, the most common of which mannitol.
2. Antibiotics: There are many such antibiotics, such as gentamicin, kanamycin, streptomycin, and ciprofloxacin, levofloxacin, ofloxacin, gatifloxacin and other fluoroquinolones, and sulfonamides drugs, anti-TB drugs, antifungal, antiviral, anti-trichomoniasis drugs so have some kidney toxicity, long-term or high-dose use can cause kidney damage.
3, contrast agents: side effects of the contrast agent is relatively large, it needs attention. Almost every contrast agents are likely to cause contrast-induced nephropathy, accounting for ICU patients with acute renal failure in 10%.

4, Chinese medicine: not all Chinese are no side effects, many Chinese have some damage to the kidneys, the kidneys can cause acute or chronic injury, currently collected nephrotoxic herbs have more than one hundred kinds. More reports such as Aristolochia, Hook, Akebia, tonkinensis, cocklebur, Clematis, Strychnos, trade routes, Croton, Alisma fangchi like. Select the traditional Chinese medicine can repair kidney essence, choose TCD therapy is recommended to choose large hospitals, such as kidney hospital micro-osmotic treatment of traditional Chinese medicine, after 26 years of clinical practice, verify the safety of Micro-Chinese Medicine and miraculous

Shijiazhuang Kidney Disease Hospital

Shijiazhuang Kidney Disease Hospital is located in Shijiazhuang city, capital of Hebei Province, which is adjacent to the capital of China, Beijing. It was founded in 1986 and his name has become more widely known in recent decades.....Read More

Shijiazhuang kidney disease hospital Address

Shijiazhuang Kidney Disease Hospital

Shijiazhuang Kidney Disease Hospital is located in Shijiazhuang city, capital of Hebei Province, which is adjacent to the capital of China, Beijing. It was founded in 1986 and his name has become more widely known in recent decades.....Read More
Kidney Disease Hospital has been established for more than 20 years of history, it is located in Shijiazhuang City Road on the 5th wing. City (museums, train station) take bus 34 and get off at the Press and Publication Bureau wing Road westbound northbound 200 meters, in the vicinity of the water park, water park from Simon only 200m.
As the largest kidney hospital in Hebei Province, a kidney specialist hospital, with its unique treatment technology, superior therapeutic effect, making the formation of a strong reputation in the kidney hospital patient friends. Why are there so many patients with kidney hospital Address search online also illustrates the impact of kidney disease hospital. So unique advantages kidney hospital in where?
First, the medical standards
Medical standards to judge a hospital's standard, that kidney hospital? We first see is the medical standards: currently the largest and most complete facilities kidney specialist hospitals, hospital construction of all three national-level hospital in accordance with the standard design and planning. 22 years of development, he has formed a set of medical, teaching, scientific research as one of the new modern nephropathy institutions. It is in these twenty years to numerous kidney patients received treatment, which also includes patients with Malaysia and other countries, enough to appear very impressive level of medical care;
Second, the expert team
Good team of experts is the basis of treatment will first see a doctor will fill a prescription, will prescribe, not a good doctor how the line! Shijiazhuang kidney specialist hospital has a dozen domestic renal disease specialists who have many years of research and experience in the treatment of treatment of kidney disease.
>>> Wang Zhanping expert online Zuozhen week, for the disease, symptoms, precautions have any questions, you can free consultation <<<
Third, the method of treatment
Treatment methods are often a symbol of a sick really good maximum likelihood, only a good way to the true meaning of good treatment of treatment of kidney disease, kidney disease hospital to establish a set of successful treatment of renal fibrosis theoretical system, diagnostic system, administration system. Three system specification due to treatment, from start blocking renal fibrosis, multiple targets targeted positioning therapy, successfully resolved the problem of recurrent kidney disease.
Fourth, service

Thirds rule, seven support, only good service, in order to give the patient a good attitude, a good environment, to a faster cure kidney disease. Kidney hospital in line with active service "and" to me so far, "the service concept," great service "promote" big effect. "Kidney hospital's unique technology allows treatment of patients every day to see the efficacy of a comprehensive, thoughtful, friendly service more It is to make the patient feel warm. Too many touching stories happened in the kidney hospital, that patient testimonials, pennants are not uncommon.

The existing basis for the work of the kidney hospital in Shijiazhuang

Shijiazhuang Kidney Disease Hospital
Chronic kidney disease and chronic renal failure is a serious harm to people's health and lives of common diseases, according to the statistics, the prevalence of American adults with chronic kidney disease 109000/100 million, or chronic renal failure prevalence rate of up to 76000/100 million, or so The prevalence of large groups, and no effective treatment, leading to chronic renal failure in 5-year survival rate is about 70% -80%, 10-year survival rate is about 35% -55%. The best treatment for kidney disease is a physician and seek common aspiration majority of patients, with the progress of regenerative medicine with stem cell-based, it is possible to find the ideal treatment of chronic renal disease from the perspective of stem cells. Stem cell transplantation in the treatment of many scholars through continuous improvement and development, thus forming a special live cell therapy disciplines. In recent years, with the rapid development of stem cell technology, stem cell transplantation in the treatment of applications for cell therapeutics has brought new vitality, open up good prospects for the development of cell therapeutics. Stem cells are self-replicating, highly proliferative and differentiation potential cell populations, these cells can divide to maintain their population size cell by cell, and can be further differentiated into various tissue cells, which constitute the body's complex organizations organs. Treatment of tissue and organ damage or dysfunction to disease, trauma, aging, and genetic and other factors provided a new way of thinking. Although stem cell therapy has a very broad clinical application, scientists from various countries also continue to make new achievements and progress, but the majority of clinical application of research results from a large gap exists. Stem cell therapy as a new means of human diseases, the exact mechanism of action remains to be further study, the clinical application of the effectiveness and safety are still the focus of attention and controversy scientists are currently a large number of experimental and clinical studies have shown that stem cell transplantation for multiple prophylactic and therapeutic effect of kidney disease, for the treatment of refractory renal disease provides new hope.
Kidney disease in the current situation and development trend of domestic and foreign:
Registration data from the US Renal Data System shows that from 1995--2004 United States began renal replacement therapy in patients with increased incidence rate of 279.5 / million population to 339.4 / million population. US ESRD (ESRD) annual incidence increased gradually recently been Markov model to predict the United States in 2015 patients with end-stage renal disease entered could reach 712,290 people. This is undoubtedly a great challenge to the existing health resources.
Data China 1999 National Dialysis Transplant Registry reports showed that patients new to dialysis that year accounted for 41.7% of the total number of dialysis patients, indirectly suggesting that the upward trend China ESRD incidence. National Health and Nutrition Examination Survey data show the United States third, CKD patients in various stages, ESRD patients only 0.6%, showing growing behind the ESRD patient, but also hidden more relatively early stage of CKD patients. No doubt there is a similar phenomenon in China. China's health system was added to the current lack of epidemiological data CKD, some doctors lack knowledge of kidney disease, resulting in a considerable part of the lack of clinical symptoms in patients with early stage CKD missed, mostly direct clinical realization, renal impairment or end-stage development only kidney was found that these patients missed the best time for treatment. The incidence of chronic kidney disease increased year by year trend, chronic kidney disease, a common treatment for hemodialysis, peritoneal dialysis does not improve renal parenchymal damage is a fundamental pathological lesion, can not prevent the occurrence of various complications, kidney transplant to treat kidney parenchymal damage from a fundamental, but a serious lack of donor and immune rejection after transplantation problem is difficult to achieve substantial breakthroughs. So the search for effective treatments is one of the key kidney disease research, the development of stem cell technology for the treatment of chronic kidney disease has brought new hope.
Stem cells are a class of self-replication of pluripotent cells, under certain conditions, it can differentiate into a variety of functional cells. Stem cell transplantation for treatment of chronic kidney disease can not only improve the dual pressures of physical and mental perennial dialysis patients brought, but also become the key to solve the source of the lack of treatment of a kidney transplant, you can replace the damaged kidney function, but also can be subjected to in vitro gene recombinantly modified, the appropriate genes into the body, which may play a better therapeutic effect, it is expected to be an important measure to stem cell transplantation as a renal replacement therapy.
Basis of existing work, characteristics and advantages:
Shijiazhuang kidney hospital technological advantages in the treatment of kidney disease can be summed up in two aspects: First, the original of the innovative use of traditional Chinese medicine - micro osmotic treatment of traditional Chinese medicine; the second is the full integration of existing kidney disease treatment technology, formed a set of three-dimensional treatment system Shijiazhuang kidney hospital characteristics, which consists of three unique core technology and a security technology, namely: the micro-based traditional Chinese medicine penetration treatment of kidney disease as the core technology features a full range of treatment, played a blocking + Repair + reconstruction results; to immunoadsorption as the core characteristics of blood purification technology, its role is to purify the blood environment for stem cell transplantation in the treatment and micro-based traditional Chinese medicine to provide a sustainable treatment relaxed environment; stem cell transplantation therapy, kidney repair + provides a new means of reconstruction. In the current Chinese medicine and Western medicine treatment for the protection of existing treatment techniques, referred to as: "Three special a security" core technology system. The huge size of the hospital, have kidney disease patients from all over the world, but also patients from foreign countries, pathogen is adequate for the treatment of carry basis. Also hospital also built in line with GMP standard laboratory, one hundred two laboratories, one thousand six laboratories, in addition to one thousand infusion chamber 2, the patient's infusion provides a clean environment. The laboratory has advanced equipment, have carried out the desired cell biology, molecular biology experiments various laboratory instruments, such as: biological safety cabinets, clean benches, carbon dioxide incubator, flow cytometry, height (often speed) Frozen (room temperature) centrifuges, fluorescence microscopy, automatic homogenizer, PCR detection systems, microplate reader, ultra-low temperature freezer, liquid nitrogen storage tank, and has a number of skilled technical personnel of cell culture experiments. A dedicated quality control personnel to each of our cells do careful quality control, our production escort to ensure the safety approval we produce every cell.
Here, we will explain in detail:
Mesenchymal stem cells [mesenchymal stem cells, MSC] is an important member of the family of stem cells derived from early development of mesoderm and ectoderm. MSC was originally found in the bone marrow, because of pluripotent hematopoietic stem cell engraftment support and promote the immune regulation and self-replication features and increasing people's attention. Such as mesenchymal stem cells in vivo or in vitro under specific induction conditions, differentiate into fat, bone, cartilage, muscle, tendons, ligaments, nerves, liver, cardiac muscle, endothelial and other cells, continuous subculture and cryopreservation still have pluripotent, it can be used as an ideal seed cells for tissue and organ repair damage caused by aging and disease. Umbilical cord tissue-derived mesenchymal stem cells not only maintain a mesenchymal stem cell biological characteristics, but also have the following advantages:
① placenta and umbilical cord stem / progenitor cells are more primitive, a stronger proliferation and differentiation.
② relatively immature immune cells, functional activity is low, do not trigger an immune response and cause graft-versus-host disease.
③ easy to separate stem cells, high purity, non-tumor cell contamination.
Cultured ④ amplification system can be unified, easy quality control.
⑤ can be made cell freezing seed, multiple use, small cell loss after freezing.
⑥ chance of infection and the spread of latent viruses and pathogens is relatively low.
⑦ when collecting on maternal and newborn without any harm and damage.

⑧ collection convenient, easy to store and transport, less ethical controversy. This umbilical cord between the mesenchymal stem cells may become bone marrow mesenchymal stem cells ideal substitute, and has greater application potential. Numerous studies indicate umbilical cord mesenchymal stem cells under certain conditions can differentiate into glomerular cells, mesangial cells, renal tubular epithelial cells of parenchymal cells, and umbilical cord mesenchymal stem cells can selectively fix found outside marrow some tubular interstitial necrosis, renal tubular structure and function recovery.

2015年6月12日星期五

Cause of kidney failure

Cause of kidney failure
Many people know that harm kidney failure, it is a very serious disease, many patients with kidney failure for failing to timely and effective treatment and death. Renal failure has always been problematic for many serious diseases, kidney failure What causes it?
1. hypertensive renal disease because it can be life-threatening, but as one of the more common complications of hypertension, has been attention. Long-term patients with high blood pressure and some people may be renal complications nephropathy (renal failure, uremia), once proteinuria in patients with hypertension, which is often the first indication of renal involvement. The kidney disease in patients with hypertension, about half in five years after the occurrence of renal failure and other complications of hypertension may also occur simultaneously.
2. diabetes with high blood pressure, as are the high incidence of sick people more widely. Diabetes also likely involving the kidney lesions, many patients with kidney failure is diabetic nephropathy evolved.

3. Acute nephritis is a common kidney disease, if not treated in time likely to develop chronic lesions to treatment more difficult, and finally there will be a possible cause of chronic renal failure. Until serum urea and creatinine rise, down to half of the normal renal function, renal failure symptoms appear. Can occur in a few months, a few years may be delayed, sometimes several years after the onset, until the terrible symptoms of uremia, just diagnosed with glomerulonephritis.

Shijiazhuang Kidney Disease Hospital

Shijiazhuang Kidney Disease Hospital is located in Shijiazhuang city, capital of Hebei Province, which is adjacent to the capital of China, Beijing. It was founded in 1986 and his name has become more widely known in recent decades.....Read More

Children with nephrotic syndrome, colds careful

Children with nephrotic syndrome, colds careful
Children with respiratory tract infections, such as colds, tonsillitis, acute pharyngitis, if not effectively control the infection in 1 to 4 weeks after it is possible to induce nephrotic syndrome. In general, children with nephrotic syndrome early symptoms of infection, it features three high and one low, that high degree of swelling, highly proteinuria, hypercholesterolemia and hypoalbuminemia. Minimal change nephrotic syndrome, the age of onset is more common in children two to six years old, and boys more than girls, vulnerable to relapse and persistent, long course.
Because child physical weakness, immune cells less than normal human immune function is not strong, so immune cells may not only failed to devour the bacteria, but the bacteria temporarily accommodate them, the body of germs and bacteria antibody binding itself into a immune complexes, with blood circulation to the kidneys, the glomerular basement membrane will be deposited, so that there is a damage to the kidneys, so that the loss of a large number of proteins, ultimately leading to nephrotic syndrome.

Nephrotic syndrome, longer course, easily repeated attack. To maintain a year and a half to two years of standard treatment. According to clinical data, some children twenty-three age of onset of the disease to 10 to 12 years of age is not good, recurrent upper respiratory tract infection is the culprit. Repeated attacks can affect long-term growth and development of children, so that extremely refractory nephrotic syndrome.

Shijiazhuang Kidney Disease Hospital

Shijiazhuang Kidney Disease Hospital is located in Shijiazhuang city, capital of Hebei Province, which is adjacent to the capital of China, Beijing. It was founded in 1986 and his name has become more widely known in recent decades.....Read More

What treatment of nephrotic syndrome do?

What treatment of nephrotic syndrome do?
What treatment of nephrotic syndrome does, this is the problem the majority of the patients with nephrotic syndrome and friends are very concerned about.
Experts pointed out that the treatment of kidney disease nephrotic syndrome principles are the following:
Ⅰ, on a regular basis as a result of urine bacterial culture and colony counting and reference drug susceptibility testing to choose the most sensitive to antibiotics. The key is to treat nephrotic syndrome in combination with antibiotics, preferably 2-3.
Ⅱ, treatment is the key to the treatment of chronic, drug treatment is not enough, even if the original treatment is effective, often can not completely remove bacteria, while cultivating a resistant, so that bacteria get respite, once the conditions are suitable, you can relapse, persistent disease.
Ⅲ, before restoring damaged kidney tissue is also caused by repeated infections key a nephrotic syndrome. Key to the treatment of chronic nephrotic syndrome to eliminate pathogens as soon as possible, to promote the early resumption of the damaged kidney tissues.
Nephrotic syndrome, complications of treatment for nephrotic syndrome may be such as edema, dyslipidemia and other symptomatic treatment:
1, for the treatment of symptoms, Western medicine Poxian its strengths in this area, including hormone drugs can relieve patients with nephrotic syndrome, urinary protein leakage in the short term, reduce the emergence of proteinuria hypoalbuminemia and other issues. Diuretics are able to quickly relieve the symptoms of a patient's body swelling.
2, drug treatment, the preferred drug for kidney damage smaller. For severe cases, kidney pathology, clinical hormones and immunosuppressive agents in combination, to minimize the side effects of drugs, and drug-drug synergy is more conducive to the treatment of disease.
3, the treatment of proteinuria and other symptoms, not simply for the sole purpose to eliminate the symptoms. Nephrotic syndrome must undergo rigorous standard treatment.

4, while the symptomatic treatment were due to treatment, so as to consolidate the disease and protect renal function.

Prevention of renal dysfunction method

Prevention of renal dysfunction method
Life, many people have large and small, kidney disease, due to the long-term fatigue and weight, the kidney is the most vulnerable to disease, one of the organs and tissues. After some human glomerular serious damage, it will lead to renal excretion of metabolic waste and regulate water and electrolyte, acid-base balance and other functions impeded, causing the body multiple system panics after clinical syndrome group, generally can be divided into chronic renal insufficiency and acute renal insufficiency. So how to prevent the disease it? Then introduce several measures to prevent chronic renal insufficiency.
First, patients with renal insufficiency have a reasonable diet, because the body's metabolism of protein in the diet comes mainly from ingredients, therefore, in order to reduce the workload of the remaining kidney, protein intake and renal excretion must adapt . Daily salt intake should vary depending on, if high blood pressure, edema, to use low-salt diet, daily 2 grams of salt.
Second, in addition, in case of other diseases must be treated in time, for hyperlipidemia, hyperglycemia, hypercalcemia and hyperuricemia patients should be appropriate and timely treatment to prevent the above factors increased kidney damage. After renal excretion of drugs may also damage the kidneys, such as gentamicin, sulfa antibiotics, such as penicillin, indomethacin, acetaminophen, as well as hormones, contrast agent.

Third, renal insufficiency patients also need a reasonable rest, adequate sleep. Patients with renal insufficiency should ensure that adequate rest and good nutrition, not to engage in activities beyond the capacity.

web