2013年11月20日星期三

About iga nephropathy care and prognosis

About iga nephropathy care and prognosis
IgA nephropathy is a kidney immune pathology same college but the clinical manifestations pathology and prognosis Shuodao great variability of primary glomerular disease, treatment should be based on their problems abroad abroad different clinicopathological given reasonable established comprehensive clinical treatment .
A hematuria or ( and ) mild proteinuria (
Two heavy proteinuria or nephrotic syndrome a mild pathological changes ( such as minor glomerular lesions mild mesangial proliferative glomerulonephritis , etc. ) glucocorticoids and cytotoxic drugs , such as availability of treatment efficacy severe pathological changes proteinuria is often ineffective controls are often included in long-term lack of progression to chronic renal heartfelt project dried poor prognosis.
Three rapidly progressive glomerulonephritis, renal biopsy pathology examination showed IgA deposition in crescentic glomerulonephritis based on clinical guidelines often has a sharp deterioration in renal function in these patients treatment should be rapidly progressive glomerulonephritis students mainly learn more example pathology revealed as cellular crescents who should be strengthened Bachelor therapy ( methylprednisolone pulse therapy cyclophosphamide pulse therapy many doctors , etc. ) If the patient has reached the dialysis indications ( please refer to section Chapter ) should be compatible with the class dialysis treatment branch most patients with poor prognosis in patients with renal function can not be restored .
Four diseases chronic glomerulonephritis may refer to the general principles of treatment of chronic recognize nephritis have to slow deterioration of renal function as main purpose to treat hypertension by Dr. positive control of hypertension is extremely important for the protection of renal angiotensin-converting enzyme inhibitors (ACEI ) have better control of blood pressure and deterioration of renal function and have reduced the role of the role of protein in the urine , but serum creatinine greater than μmol / L generally not in favor of re- application of Chinese ACEL recent studies have shown that high doses of some long-chain ω- rich multi- poly- unsaturated fatty acids in fish oil taking months to years of delay have better IgA nephropathy worsening kidney function and reduce the role of protein in the urine , but more research is yet further validation .
Recent evidence suggests that evidence-based medical papers glucocorticoids for urine protein greater than lg / d in patients with normal renal function, lower urinary protein studying deterioration of renal function and prevention role ; For renal dysfunction serum creatinine <μmol / L in patients with glucose corticosteroids in combination with cytotoxic drugs can significantly delay the department deterioration of renal function in short current study showed for the table to be transplanted now chronic nephritis IgA nephropathy CY prize seems to be more active this view that more research needs to be confirmed .
Nursing
1 , pay attention to health , keep the mouth and skin clean , bathe, wash brush your teeth, wash locker .
2 , always observe the patient's body temperature , urine color changes, abnormal timely treatment .
3 , enhance nutrition, improve physical fitness , to avoid repeated infections. But not for eating spicy foods and milk .
4 , children IgA nephropathy patients should pay attention to warm cold , avoid cold bath , sweating when the wind , ready to change clothes , the maximum to avoid colds and other infectious diseases.

5 , should be checked regularly to the hospital , to prevent the further development of disease ( may have no clinical manifestations ) .

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