Proteinuria is not all morbid functional proteinuria and pathological proteinuria points. Functional proteinuria , also known as physiological proteinuria , is the emergence of temporary proteinuria in healthy people . More common in young people under the influence of strenuous exercise , fever , high temperature, exposure to cold , stress and other factors , renal vascular spasm or congestion, resulting in glomerular filtration membrane permeability-increasing protein leaving a large number of " slipping through the net ." Normal urine of pregnant women may be a slight increase in protein , which increase with postural and renal flow , glomerular filtration rate increases related. Proteinuria functional proteinuria after the lifting of incentives will go away . It is also called a transient reversible proteinuria or albuminuria .
Pathological proteinuria refers to a system or organ of human disease caused by the occurrence of persistent urinary protein . General 24-hour urine protein more than 150 mg. Common in three cases:
Glomerular proteinuria : for various reasons caused the glomerular capillary wall injury ( such as immune damage ) , the load reduction or loss , resulting in glomerular permeability . Multiple plasma protein after filtration, tubular reabsorption of excess capacity , resulting in proteinuria. Such as acute and chronic nephritis, lupus nephritis , diabetic nephropathy .
Tubular proteinuria : renal tubular lesions or renal tubular dysfunction , decreased or reabsorption of proteins secreted protein increased, resulting in increased urine protein . Such as renal tubular acidosis , kidney disease caused by analgesics , antibiotics, and other manifestations of renal toxicity .
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