2014年4月14日星期一

Allergic purpura nephritis how else ?

Are allergic purpura allergic purpura nephritis secondary lesions, is a systemic autoimmune disease . In patients with allergic purpura , about one-third or more kidney damage can occur , which Youyi children aged less common. Therefore, understanding of allergic purpura nephritis is particularly important, while about allergic purpura nephritis induced factors manipulated to prevent the occurrence of allergic purpura nephritis .
What is the cause of allergic purpura ?
Most patients have flu or food to eat seafood ( such as fish, shrimp, crabs and clams , etc. ) before the onset of the case . Is due to the small number of children induced a guard such as antibiotics, iodine amine, isoniazid , salicylates , barbiturates and other drugs , and iodide . This occurs due to respiratory infection or pioneer seafood consumption of food, medicines and a red rash illness , called " purpura " clinically .
HSP expression
In addition to patients with allergic purpura hemorrhagic rash red outside , many accompanied by abdominal pain, nausea and vomiting , swollen lymph nodes and other symptoms. When patients rash usually 4 to 8 weeks , the kidneys will be damaged to some extent . Allergic purpura nephritis patients with clinically isolated hematuria appeared for the outstanding performance , some patients with proteinuria, edema. Purpura nephritis How did it happen ?
When the body's immune function is normal, non-self antigens can generate both humoral and cell-mediated immunity , the body play a role in immune cherish . When the immune dysfunction , outside bacteria, seafood , drugs , etc. , then can cause allergic reactions, autoimmune disease or immunodeficiency diseases , to the detriment of human health. These in vivo antigen antibody binding virulence factors produced after formation of immune complexes, these immune complexes in the glomerular most easily precipitated , thereby initiating the process of renal fibrosis . Children 's immunity is weaker than adults, their natural resistance to disease worse . Especially in the cold season or cold, children with allergic purpura cold easily occur . After the invasion of children's cold body , is likely to form immune complexes in vivo antibody which acts on the kidneys, resulting in the occurrence and aggravation of allergic purpura , it is especially important to prevent colds .

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