Be cautious of a Bite of Kidney Diseases

With the increasing health consciousness of people,many families will prepare medical kits for themselves. Various kinds of medicines in the Drug Store can benefit residents on the one hand,but on the other,all medicines have their side effects,some drugs may contain renal toxic ingredients and without proper intake drug-induced kidney diseases can be caused. This article discusses several kidney damaged drugs and hopes readers be cautious of a Bite of Kidney Diseases.
Non-steroid anti-inflammatory drug(NSAID)
NSAID has been one of the most commonly used drugs,which has been widely used in the treatment of osteoarthritis,rheumatoid arthritis and other rheumatic autoimmune diseases. It can also be applied in the relief of fever and aches. Frequently used medicines of this kind are aspirin, acetylsalicylic acid,ibuprofen,indometacin and phenylbutazone. It the NSAID is used in a small dose in a short time,the side effects are low;otherwise renal function damage can be resulted in. The elderly and kidney disease patients who are at a high risk should avoid use of NSAID or choose other alternative medicines directed by a physician. People who take NSAID for long should do regular examination of renal function.
Antibiotics
Because of easy access to antibiotics in the Drug Stores,many patients who are suffered with cold,fever and urinary tract infections will take them at random even without learning instructions. However,excessive dosage and long duration may lead to kidney damage and seriously acute allergic intestinal nephritis occurs since patients are allergic to antibiotics,and those patients will often be diagnosed with albuminuria,blood urine and renal dysfunction. Medicines such as aminoglycoside,quinolones,tetracycline,rifampin and aktisol-weiss are often used in the clinical and may lead to kidney damage. These medicines should be used with caution especially for those who already have kidney diseases.
Antihypertensive drugs such as “captopril”and “sartan”
These drugs are antihypertensives and have been proved to be effective in reducing albuminuria and postponing kidney damage,they are often adopted in treating kidney diseases. However,this kind of medicines can reduce GFR,when the serum creatinine level is more than 265 μmol/L,abnormal rise of serum creatinine can be induced. If the range of serum creatinine is increased by more than 30% when the drugs are used for 2 to 4 weeks,and renal ischaemia occurs,the medicines should be stopped timely. Besides,when such drugs and non-steroid anti-inflammatory drugs are used jointly,the chance of renal injury is greatly increased. This drug is contraindicated in patients with low blood pressure,severely diarrhea,heavy vomiting and double renal artery stenosis.