Among life , suffering from kidney failure increasingly large groups , and
for chronic renal failure patients, the clinical emergence of anemia is a normal
phenomenon , then what is the reason for it, by the following article let us
briefly understand look.
Chronic renal disease is the most common clinical one, this disease usually
occurs when most of the anemia of chronic renal failure patients will appear the
phenomenon in general, which mainly includes the following aspects :
First, anemia is the most common cause of erythropoietin decrease , experts
said , erythropoietin primarily by glomerular nearly spherical cells, medullary
interstitial cells. Chronic renal failure, in addition to the kidneys produce
erythropoietin damaged parts , the lower the oxygen affinity of hemoglobin ,
hemoglobin oxygen utilization unit increased relatively severe renal ischemia ,
resulting primarily stimulate erythropoietin reduced, resulting in produce
erythropoietin significantly reduced . There are toxins bone marrow suppression
, chronic renal failure, certain toxic substances accumulate in the blood has a
direct inhibitory effect on the bone marrow , leading to hematopoietic
dysfunction.
One reason addition, if the red blood cell destruction in patients with
chronic renal anemia is caused by the increase , which is high due to uremia RBC
Polyamines cause shortened life hyperlipidemia , autolysis occurs , metabolic
disorders erythrocytes and erythrocyte fragility uremia , causing red blood cell
autolysis, microvascular disease makes mechanical damage and destruction of red
blood cells , hypersplenism .
As well as the loss of red blood cells increases, chronic gastrointestinal
bleeding or gastrointestinal hidden under the long term , regular laboratory
tests or blood loss residual blood dialyzer , the situation can aggravate
chronic renal failure patients. May also be due to other diseases cause , such
as hypertension , diabetes and so on , some diseases may affect the
hematopoietic function, may also affect the body's absorption of nutrients ,
leading to malnutrition induced by this phenomenon.
Xiao Bian Message : The cause of anemia in chronic renal failure patients
understand the phenomenon of post , remember when the treatment of chronic renal
disease , symptomatic treatment must be for the cause , so as to restore health
faster . I wish you health .
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