(1) plasma exchange and immunoadsorption: This therapy can theoretically be removed from the plasma antigen and antibody immune complexes, and improving phagocytosis network head endothelial system, it can achieve the purpose of controlling disease activity. It can be used to diffuse proliferative lupus nephritis activity, and can be applied to the combined impact of hormone therapy immunosuppressants still can not control the activities of the disease, and kidney function when abrupt deterioration. For the adsorption of DNA immunosuppressive therapies currently under test.
(2) cyclosporine A (CSA): Some patients showed that the drug could protect the function and histology from kidney, prevent kidney immune complex deposition and prevent the onset of nephritis and proteinuria produce, but does not reduce the anti-DNA the level of antibiotics or loop composite body, after the withdrawal relapse, and liver and kidney toxic side effects, efficacy is uncertain.
(3) being studied in the treatment methods are: thromboxane receptor blockers, r- and anti-lymphocyte globulin antiserum (ACG), the antibiotic chest cell antiserum (ATG), anti-CD4 monoclonal antibody and the like.
(4) Other: anticoagulant therapy with heparin. Its anticoagulant, against the antidiuretic hormone (ADH), complement the role of the glomerular basement membrane negative charge, and can still improve renal microcirculation, diuretic and reducing the role of protein leakage, the usual dose of 100 mg / day, divided into two subcutaneous injection. Against platelet aggregation medicinal dipyridamole 50-100 mg three times a day orally. Reduce high glomerular filtration with ACEI, such as Lotensin 10 mg -40 mg / day, and simultaneously reduce high blood pressure.
Shijiazhuang Kidney Disease Hospital
Shijiazhuang Kidney Disease Hospital is located in Shijiazhuang city, capital of Hebei Province, which is adjacent to the capital of China, Beijing. It was founded in 1986 and his name has become more widely known in recent decades.....Read More
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