Diagnosis of diabetic nephropathy from which to proceed

What is the cause of diabetic nephropathy? Perhaps some people to understand, is not this kind of diabetes complications, what, indeed, in short, diabetic nephropathy, diabetes and kidney disease are mutually reinforce each other to promote the development of the disease. Therefore, the diagnosis of diabetic nephropathy, and comprehensive consideration of both the symptoms and the condition of both the history and here's a look:
Currently, the diagnosis of diabetic nephropathy were diagnosed mainly in three aspects.
First, the diagnosis of diabetic nephropathy from medical history and symptoms to diagnosis of diabetic nephropathy:
Patients with a history of diabetes, and kidney damage and the extent of the clinical manifestations of glomerular sclerosis were positively correlated.
Microalbuminuria occurs when diabetes has more than 5 to 6 years, the clinical diagnosis of early diabetic nephropathy, without any clinical manifestations;
About 80% of patients over 10 years of clinical development of diabetic nephropathy, namely urinary protein excretion greater than 0.5g / 24h, hematuria usually no obvious clinical manifestations of edema, hypertension; once persistent proteinuria appeared, accompanied by loss of appetite, nausea and vomiting, anemia, suggesting that chronic renal insufficiency have occurred.
Diagnosis of diabetic nephropathy from medical aspects can also be used to diagnose diabetic nephropathy:
Varying degrees of hypertension, edema, can occur in severe clinical symptoms of ascites, pleural effusion and multiple diabetic retinopathy, etc. These are all diabetic nephropathy.
Final diagnosis of diabetic nephropathy can be diagnosed from the inspection aspects:
A urinary albumin excretion (UAE) 20 ~ 200μg / min, is an important indicator of early diagnosis of diabetic nephropathy; sustained when UAE greater than 200μg / min or routine examination of urine protein positive (urine protein greater than 0.5g / 24h), namely diagnosis for diabetic nephropathy. Urine general change is not obvious, more white blood cells when prompted urinary tract infection; large number of red blood cells, suggesting that there may be other causes of hematuria.
2 fundus examination, fundus when necessary for fluorescence imaging, visible micro-aneurysms and other diabetes retinopathy.
3 radionuclide dynamic renal glomerular filtration rate (GFR) and B-increase measure kidney volume increase, in line with early diabetic nephropathy. When uremia GFR decreased, but not significantly reduced kidney volume often.
4 Qualitative urine is a simple method of screening for diabetes, but can occur in diabetic nephropathy false negative or false positive, so the blood glucose is the main basis for diagnosis.

5. advanced diabetic nephropathy, creatinine clearance rate and blood urea nitrogen, creatinine increased.