Systemic lupus erythematosus is a multi-system disease damage, presenting
symptoms are varied, some patients with a basic organ damage based, and
performance systems for some of the symptoms, the patient again some other organ
systems damage to the main, it is also manifested as symptoms of another system,
sometimes many organs can be damaged at the same time, the condition is more
complex, so for patients with systemic lupus erythematosus in terms of
performance is not a fixed pattern. To sum up can be divided into renal
manifestations and kidney damage performance.
(1) the performance of systemic lupus erythematosus was the diversity beyond
the kidney can no obvious symptoms, and test results only erythematosus cells or
positive antinuclear antibodies until fulminant dangerous. But in general the
patient on medical history and clinical manifestations, more damage with
multiple joint pain, fever, rash and kidney, lung, cardiovascular and blood
system. The main signs and symptoms include:
① patients with fever, hot-type variable, can be divided into long-term
unexplained fever, also for the heat.
②60% of patients may present both cheeks and bridge of the nose like a
butterfly-shaped rash, erythema subsided after generally do not leave scars and
pigmentation. The rash erythema often encountered after the sun or ultraviolet
light irradiation increased, this is called light sensitive. 50% of patients
seen hair loss. Also visible urticaria, erythema discoid body, around the nail
erythema purple, purple haemorrhage, oral and nasal ulcers.
③90% of patients with joint pain, common in the small joints of the limbs,
were multiple. About 10% of patients may have mild joint deformity.
④ pericarditis patients with active systemic lupus erythematosus may occur up
to 60%, usually for brief mild clinical manifestations. 10% of patients may have
myocarditis performance.
⑤40% -46% of patients with pleurisy can occur, such as chest tightness,
wheezing.
⑥50% -75% of patients may have anemia; leukopenia 60% of patients,
particularly lymphocytes decreased; platelets can be reduced.
⑦ some patients may have to demonstrate their nervous system. However, its
performance is complex and diverse, usually mental disorders such as depression,
psychosis, etc., other visible epilepsy, migraine, paralysis, disease,
peripheral neuropathy and retinopathy.
⑧ other visible irregular menstruation, premenstrual symptoms, especially
migraine. Some patients may occur painless lymph nodes, parotid gland
enlargement.
(2) Approximately 70% of patients with varying degrees of renal impairment
clinical manifestations, insidious onset may also be abrupt, the course is
generally longer, with or without symptoms. Urinalysis is not normal, often
hematuria and (or) proteinuria. Edema and hypertension, is also one of the
common performance.
Late lupus nephritis urea disease can occur, when the clinical manifestations
of lupus activity may disappear or not typical.
If you have any questions you can consult online Shijiazhuang kidney hospital
doctor.kidneyservice@hotmail.com
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