Symptoms of renal hypertension are there?
Hypertension, renal hypertension symptoms also exists, not repeat them. Here
are just some of the special aspects of the performance of renal hypertension
make a profile.
Compared with the same level of essential hypertension, renal hypertension
essential hypertension compared with more progress to malignant hypertension,
which occurs in approximately 2-fold. Which, IgA nephropathy, especially
sclerosis, or hardening of IgA nephropathy secondary to malignant hypertension,
especially common. Also, comparison with primary malignant hypertension, renal
parenchymal malignant hypertension worse prognosis, some authors statistics, the
former five-year kidney survival rate was 60%, while the latter one and a half
years renal survival is only 4%.
Renal hypertension is often severe retinopathy, cardiovascular and
cerebrovascular complications occur more often. This is because in addition to
hypertension, other cardiovascular risk factors often compound the presence of
renal parenchymal disease, such as lipid metabolism disorder nephrotic syndrome,
and glucose metabolism during diabetic nephropathy, anemia, renal insufficiency,
and hyperuricemia disease, high homocysteine, uremic toxins, metabolic
acidosis, and micro-inflammatory state, these complex factors will significantly
increase the incidence of cardiovascular complications.
In this, the need to emphasize that especially affect renal hypertension and
chronic kidney disease on the basis of renal disease progression. Chronic renal
disease was before the glomerular arterioles diastolic state, the system is very
easy to pass the glomerular hypertension, resulting in glomerular hypertension,
high perfusion and high filtration, this "three high" that can accelerate the
remaining glomerulosclerosis; Meanwhile, long-term high blood pressure can lead
to kidney arteriosclerosis, including hyaline afferent arterioles, interlobular
artery and arcuate artery intimal thickening of the muscle, so that small artery
wall thickening luminal narrowing , secondary to renal ischemia
Damage (glomerular ischemic collapse was to ischemic sclerosis, tubular
atrophy and renal interstitial fibrosis). Therefore, renal hypertension is not
well controlled will significantly accelerate renal parenchymal disease
progression, creating a vicious cycle.
Urinary protein quantity glomerular disease, hypertension and kidney damage
effect is more obvious, because both effects overlay. Now known proteinuria,
especially in a large number of glomerular proteinuria can be caused by a high
pressure, high perfusion and high filtration promote glomerulosclerosis; And,
filtered proteins (including complement and growth factors, etc.) and in
combination with protein certain substances (including lipid and iron, etc.)
after being tubular reabsorption, tubular cells can activate the release of
pathogenic factors (such as transforming growth factor β, etc.) to promote renal
interstitial fibrosis. Therefore, in patients with renal hypertension with
proteinuria, more should be strictly controlled hypertension.
The main points of renal hypertension diagnosis are: patients generally
younger; previous history of kidney disease; limbs often clammy, pale and more;
higher diastolic blood pressure in a small pulse, blood pressure is
characterized by small fluctuations; often nephropathy signs such as anemia,
hematuria, proteinuria, nocturia, varying degrees of renal damage; B ultrasound
showed renal parenchyma diffuse lesions, such as renal cortical thinning.
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