2014年7月11日星期五

What are the symptoms of IGA nephropathy?

What are the symptoms of IGA nephropathy?
IGA nephropathy differential diagnosis must first understand what the symptoms of IGA nephropathy?
IgA nephropathy symptoms:
1, episodes of gross hematuria: It is usually in the upper respiratory tract infections (tonsillitis), after infection, even after vaccination or strenuous exercise acute gastroenteritis, osteomyelitis, peritonitis, such as herpes zoster. The most common upper respiratory tract infection with a very short time intervals (24 to 72 hours, even a few hours can be as short) after gross hematuria, so it was called pharyngitis sync hematuria. Gross hematuria continued for several hours to several days, usually less than three days. There are repeated episodes of gross hematuria characteristics.
2, microscopic hematuria with / without asymptomatic proteinuria: mostly in checks and screening for students to join the army, marriage and other routine health inspection found for biopsy and diagnosis. For children and young people with IgA nephropathy major clinical manifestations.
3, proteinuria: IgA nephropathy Most patients showed mild proteinuria, ECTkey = 24-hour urinary protein excretion 24-hour urinary protein excretion nephrotic syndrome.
Rapidly progressive nephritic syndrome: not common. Many patients with persistent hematuria, proteinuria. Abrupt deterioration of renal function in a short time, may have edema and mild to moderate hypertension. Glomerulonephritis, both acute and chronic pyelonephritis. If we can get effective treatment of acute, almost always cured, if it is difficult to turn into a chronic cure. Nephrotic syndrome, IgA nephropathy, purpura nephritis is generally difficult to cure. Nephritis, uremia stage renal disease often appear, if not treated, most patients die within six months.
IGA nephropathy and identification of other illnesses:
1, acute post-streptococcal glomerulonephritis:
With IgA nephropathy also prone to young men, hematuria upper respiratory tract infection (or acute tonsillitis), the may have proteinuria, edema and hypertension, or renal damage. The difference between the two is that patients with IgA nephropathy after a very short interval of upper respiratory tract infection (1-3 days) that hematuria, elevated serum IgA levels in some patients. The acute nephritis often seen in about 2 weeks after streptococcal infection clinical symptoms of acute nephritic syndrome, decreased serum C3, IgA levels were normal can help identify.
2, non-IgA mesangial proliferative glomerulonephritis:
Non-IgA mesangial proliferative glomerulonephritis incidence in China, about 1/3 of the patients presented with hematuria. Clinically difficult to identify with IgA nephropathy. Required by the immune pathology biopsy to identify.
3, thin basement membrane nephropathy:
Thin basement membrane nephropathy main clinical manifestations of recurrent hematuria, about 1/2 of the patients had a family history. Clinical manifestations of benign process. Urine Pf4 levels of IgA nephropathy can help with identification. Must rely on electron microscopic examination and biopsy IgA nephropathy identification.
4, allergic purpura nephritis:

Patients may present with hematuria or microscopic hematuria. Renal biopsy may have the same extensive mesangial IgA deposition with primary IgA nephropathy. But purpura kidney patients often typical skin purpura, abdominal pain, arthralgia performance.

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