What are the symptoms of IGA nephropathy?
IGA nephropathy differential diagnosis must first understand what the
symptoms of IGA nephropathy?
IgA nephropathy symptoms:
1, episodes of gross hematuria: It is usually in the upper respiratory tract
infections (tonsillitis), after infection, even after vaccination or strenuous
exercise acute gastroenteritis, osteomyelitis, peritonitis, such as herpes
zoster. The most common upper respiratory tract infection with a very short time
intervals (24 to 72 hours, even a few hours can be as short) after gross
hematuria, so it was called pharyngitis sync hematuria. Gross hematuria
continued for several hours to several days, usually less than three days. There
are repeated episodes of gross hematuria characteristics.
2, microscopic hematuria with / without asymptomatic proteinuria: mostly in
checks and screening for students to join the army, marriage and other routine
health inspection found for biopsy and diagnosis. For children and young people
with IgA nephropathy major clinical manifestations.
3, proteinuria: IgA nephropathy Most patients showed mild proteinuria, ECTkey
= 24-hour urinary protein excretion 24-hour urinary protein excretion nephrotic
syndrome.
Rapidly progressive nephritic syndrome: not common. Many patients with
persistent hematuria, proteinuria. Abrupt deterioration of renal function in a
short time, may have edema and mild to moderate hypertension.
Glomerulonephritis, both acute and chronic pyelonephritis. If we can get
effective treatment of acute, almost always cured, if it is difficult to turn
into a chronic cure. Nephrotic syndrome, IgA nephropathy, purpura nephritis is
generally difficult to cure. Nephritis, uremia stage renal disease often appear,
if not treated, most patients die within six months.
IGA nephropathy and identification of other illnesses:
1, acute post-streptococcal glomerulonephritis:
With IgA nephropathy also prone to young men, hematuria upper respiratory
tract infection (or acute tonsillitis), the may have proteinuria, edema and
hypertension, or renal damage. The difference between the two is that patients
with IgA nephropathy after a very short interval of upper respiratory tract
infection (1-3 days) that hematuria, elevated serum IgA levels in some patients.
The acute nephritis often seen in about 2 weeks after streptococcal infection
clinical symptoms of acute nephritic syndrome, decreased serum C3, IgA levels
were normal can help identify.
2, non-IgA mesangial proliferative glomerulonephritis:
Non-IgA mesangial proliferative glomerulonephritis incidence in China, about
1/3 of the patients presented with hematuria. Clinically difficult to identify
with IgA nephropathy. Required by the immune pathology biopsy to identify.
3, thin basement membrane nephropathy:
Thin basement membrane nephropathy main clinical manifestations of recurrent
hematuria, about 1/2 of the patients had a family history. Clinical
manifestations of benign process. Urine Pf4 levels of IgA nephropathy can help
with identification. Must rely on electron microscopic examination and biopsy
IgA nephropathy identification.
4, allergic purpura nephritis:
Patients may present with hematuria or microscopic hematuria. Renal biopsy
may have the same extensive mesangial IgA deposition with primary IgA
nephropathy. But purpura kidney patients often typical skin purpura, abdominal
pain, arthralgia performance.
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