Check renal function and serum creatinine is the most commonly used
indicators. Normal serum creatinine measure each hospital is not the same, in
general normal serum creatinine criteria: 44-133umol / L, when serum creatinine
exceeds 133umol / L mean renal injury, has renal insufficiency, kidney failure.
(133umol / L or more inflammatory injury period, 186umol / L for renal injury
period, 451umol / L for renal failure).
A normal value
Men: 44-133umol / L
Female: 70-108umol / L
Pediatric: 25 ~ 69umol / L.
Creatinine values higher than normal is called creatinine, creatinine,
including serum creatinine and urine creatinine, but creatinine more meaningful
measure of kidney function. So in general it refers to the high creatinine serum
creatinine higher. Normal serum creatinine measure each hospital is not the
same, in general normal serum creatinine criteria: 44-133umol / L, when serum
creatinine exceeds 133umol / L mean renal injury, has renal insufficiency,
kidney failure. (133umol / L or more inflammatory injury period, 186umol / L for
renal injury period, 451umol / L for renal failure).
Normal serum creatinine: Men 44-133umol / L (0.8 ~ 1.2mg / dL)
2 value is high Cause
Changes in serum creatinine concentration mainly by glomerular filtration
capacity (glomerular filtration rate) to decide. Filtration capacity decreased,
the creatinine concentration. Most of mean serum creatinine higher than normal
kidney damage, serum creatinine can more accurately reflect the situation renal
impairment is not sensitive indicators. Because the glomerular filtration rate
decreased to 1/3 of normal, serum creatinine was significantly increased.
Meaning that, because human kidney metabolism ability, when kidney damage is
generally less obvious discomfort, so a lot of people when the real nausea,
vomiting, dizziness, in fact, have been severely injured kidney, serum
creatinine at this time also began to rise significantly .
3 causes of low value
Description of renal function in patients with serum creatinine higher when
there is a problem, the ability of the kidneys decreased metabolic waste, some
of the body of harmful toxins not normally excreted, then what is opposed to low
serum creatinine reason? Low serum creatinine is due by the kidney in violation
of various causes, the first impaired renal intrinsic cells transformed
phenotype, the formation of pathological changes, stimulate kidney fibroblasts
into myofibroblasts converted, and at the same time violations and stimulate the
inherent normal kidney tissue, the occurrence of the same disease, thus forming
a kidney from point to plane, from local to global, expanding the spread of
excitation type process to enter the device quality injury period (ie renal
injury period) , this time due to the continuous renal damage, which excrete
waste function decreased, causing a creatinine accumulation of toxins in the
body, which appears in the blood creatinine, blood urea nitrogen increased,
decreased urine creatinine, renal filtration rate decline. At the same time
patients will have high blood pressure, high degree of swelling and other
symptoms elsewhere in the body
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