2014年10月26日星期日

Normal serum creatinine

Check renal function and serum creatinine is the most commonly used indicators. Normal serum creatinine measure each hospital is not the same, in general normal serum creatinine criteria: 44-133umol / L, when serum creatinine exceeds 133umol / L mean renal injury, has renal insufficiency, kidney failure. (133umol / L or more inflammatory injury period, 186umol / L for renal injury period, 451umol / L for renal failure).
A normal value
Men: 44-133umol / L
Female: 70-108umol / L
Pediatric: 25 ~ 69umol / L.
Creatinine values ​​higher than normal is called creatinine, creatinine, including serum creatinine and urine creatinine, but creatinine more meaningful measure of kidney function. So in general it refers to the high creatinine serum creatinine higher. Normal serum creatinine measure each hospital is not the same, in general normal serum creatinine criteria: 44-133umol / L, when serum creatinine exceeds 133umol / L mean renal injury, has renal insufficiency, kidney failure. (133umol / L or more inflammatory injury period, 186umol / L for renal injury period, 451umol / L for renal failure).
Normal serum creatinine: Men 44-133umol / L (0.8 ~ 1.2mg / dL)
2 value is high Cause
Changes in serum creatinine concentration mainly by glomerular filtration capacity (glomerular filtration rate) to decide. Filtration capacity decreased, the creatinine concentration. Most of mean serum creatinine higher than normal kidney damage, serum creatinine can more accurately reflect the situation renal impairment is not sensitive indicators. Because the glomerular filtration rate decreased to 1/3 of normal, serum creatinine was significantly increased. Meaning that, because human kidney metabolism ability, when kidney damage is generally less obvious discomfort, so a lot of people when the real nausea, vomiting, dizziness, in fact, have been severely injured kidney, serum creatinine at this time also began to rise significantly .
3 causes of low value

Description of renal function in patients with serum creatinine higher when there is a problem, the ability of the kidneys decreased metabolic waste, some of the body of harmful toxins not normally excreted, then what is opposed to low serum creatinine reason? Low serum creatinine is due by the kidney in violation of various causes, the first impaired renal intrinsic cells transformed phenotype, the formation of pathological changes, stimulate kidney fibroblasts into myofibroblasts converted, and at the same time violations and stimulate the inherent normal kidney tissue, the occurrence of the same disease, thus forming a kidney from point to plane, from local to global, expanding the spread of excitation type process to enter the device quality injury period (ie renal injury period) , this time due to the continuous renal damage, which excrete waste function decreased, causing a creatinine accumulation of toxins in the body, which appears in the blood creatinine, blood urea nitrogen increased, decreased urine creatinine, renal filtration rate decline. At the same time patients will have high blood pressure, high degree of swelling and other symptoms elsewhere in the body

没有评论:

发表评论

web