Prednisone treatment of lupus nephritis effect you?

Prednisone treatment of lupus nephritis effect you? Prednisone treatment of lupus nephritis is mainly eliminated by the immunosuppressive effects of clinical symptoms, the effect is worth for sure, but the majority of patients with late effects should know: easy to relapse. Described in detail below.
Prednisone treatment of lupus nephritis mainly through:
1 anti-inflammatory effect: to reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. Hormone suppression of inflammatory cells, including macrophages and leukocytes at sites of inflammation, the accumulation, and inhibition of phagocytosis, lysosomal enzyme release and synthesis and release of chemical mediators of inflammation.
2 immunosuppressive effects: to prevent or inhibit the cell-mediated immune response, delayed hypersensitivity reactions, reduction of T lymphocytes, monocytes, eosinophils number, the ability to reduce the binding of immunoglobulin to cell surface receptors and inhibit the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response. Immune complexes can be reduced through the basement membrane, and can reduce the concentration of complement components and the immunoglobulin.

Many patients taking prednisone there is a certain effect, but the side effects are great, but palliatives. Mainly due to the prednisone can suppress the immune response, but can not clear the immune complexes, can not repair damaged renal intrinsic cells, so often there will be repeated illness phenomenon. It is recommended to consider the side effects of other drugs, kidney hospital on the basis of this existing domestic immunosuppressive drugs and technology, the introduction of foreign latest, more suitable for a range of low immunosuppressive therapy effective drug side effects and technology, first, to block the immune response, followed by immunological tolerance. Immune complex deposition in the kidney, the Department may be completely eliminated in a short time, so let's efforts to adapt to human pathogenic foreign matter deposited on the fact that the kidney tissue to stop the immune response. Then is to get the immune mediation stage, adjustments to work within the environment of the immune system, enhance human immunity. On the basis of immune regulation, based on the introduction of protective immunity in patients with stage repair podocytes and mesangial cells. The last resort is immune clearance, which should take appropriate immunosorbent assay based on the actual condition of the patient, plasmapheresis and blood purifier.