2014年11月25日星期二

Hazard lupus nephritis

For the treatment of lupus nephritis, use of immunosuppressive drugs to control lupus activity are important, but just focus on the treatment of lupus renal protection neglect may ultimately result in treatment failure, renal insufficiency. In fact, because of kidney damage caused by lupus activity if more serious, even inactive lupus, kidney disease can continue to increase, hardening of the kidney, leading to renal insufficiency. Therefore, in the course of treatment of lupus nephritis, we must pay attention to protect the kidneys, to avoid renal insufficiency. If some patients because of recurrent lupus activity or delayed treatment, may have varying degrees of renal insufficiency treatment, they should not try to make the development of kidney damage. Then there are those factors that can aggravate kidney damage? The following is a summary of Nephrology expert Shijiazhuang kidney disease hospital, and I hope to patients to help a friend.
The first is the high blood pressure. Lupus nephritis is often complicated by hypertension, and high blood pressure is the biggest risk factor for worsening renal function, patients with lupus nephritis and therefore must pay attention to whether the blood pressure, such as high blood pressure must be strictly controlled.
Followed by proteinuria. Proteinuria and glomerular damage not only reflect, but also cause tubulointerstitial damage, is one of the risk factors that lead to kidney disease progression. Reduce urinary protein, can reduce the damage to the kidneys, play a role in protecting the kidneys. Angiotensin-converting enzyme inhibitors such as Lotensin and angiotensin receptor antagonists such as Diovan and other drugs, can reduce proteinuria and slow down kidney sclerosis, played the role of protecting the kidneys. Such as proteinuria persists, even with normal blood pressure, may also be used of these drugs.
Third: nephrotoxic drugs. Some drugs often have damage to the kidneys, such as sulfonamides, card multiple antibiotics kanamycin, gentamicin, polymyxin B, etc; traditional Chinese medicine (especially manshuriensis, defense has been, etc.); analgesic agents. Try to avoid the use of unnecessary drugs, should not increase your kidney damage.
Fourth: infection. In the course of treatment of lupus nephritis (especially within the first few months of treatment) prone to infection. Infection often leads to relapse or exacerbation, which in daily life should be taken to prevent, avoid going to crowded places, to reduce the incidence of infection. Once infection occurs, treatment should be timely, timely medication.
Fifth: obesity. Obesity is a major problem at present hazards to public health worldwide. Obesity is not only hyperlipidemia, hypertension, coronary heart disease risk factors, can also increase proteinuria, increased kidney damage. If lupus patients with obesity lose weight should pay attention to maintain ideal body weight can reduce proteinuria and slow the progression of the disease.

Of course there are other factors, such as heart failure, acidosis, electrolyte imbalance, high cholesterol, etc., in the course of treatment should be corrected.

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