2015年2月11日星期三

What are the symptoms of lupus nephritis?

Systemic lupus erythematosus is an autoimmune disease involving many systems and many organs, if the kidney is involved, it is lupus nephritis erythematosus .According general examinations, patients involving the kidneys repesente about 90% .According the pathogenesis of lupus erythematosus, the genetic element is a significant trend, the environmental factor plays an important role in triggering such virus infection, the drug factor and sunlight .The woman with lupus represent about 90% in the crowd with nephropathy .All older or younger patients accompanying systemic pathological changes especially fever, joint inflammation, skin rash, and blood rushed increases obviously it is better to do a conventional examination and immune serum examination which is relative with lupus erythematosus, for the precise diagnosis .The pathological change is closely related to the prognosis, kidney involved and progressive renal injury are the main reasons of death .So it is important to renal biopsy for erythematosus lupus nephritis patients.
As clinically observed, there is 70% of lupus erythematosus patients have symptoms of kidney damage, only appear in a different time. Generally, lupus nephritis kidney lesion is a little late, maybe after six months to two years. But there are the first patients have symptoms of edema and urine protein, and it should alert the developing systemic lupus erythematosus in systemic lupus nephritis .After the diagnosis, one must take attention to the symptoms of kidney lesions. The symptoms of renal injury lupus erythematosus about contain a series of symptoms of glomerulus and tubular interstitial renal .the process of vascular disease is usually long, whether or not the symptoms aware, but renal injury may be a symptom effective clinical .L'œdème is a common clinical manifestations, as is often the main reason for receiving the bedwetting .Augmentation treatment is one of the primary symptoms erythematosus lupus nephritis, it often reflects dysfunction concentration urine .There was about one sixth of patients with lupus erythematosus nephritis have various degree of reduction in renal function .The renal lesions are divided into four stages:
1. nephritis syndrome, the symptoms are similar with acute nephritis
2. nephropathy syndrome, obvious edema, a large number of protein urine, hypoproteinemia
3. renal dysfunction of chronic nephritis is similar with chronic glomerulonephritis, have edema, urine protein, urine, blood, continued pressure, and accompanied with anemia and progressive renal dysfunction .It can cause uremia in a short time.

4. Type radical, the disease state is progressing rapidly, continuous fever, urine protein, urine blood, increased amount of blood cells like â tube, rapid renal dysfunction.

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