Have I Got Kidney Failure?

Many diseases have the potential to arouse Kidney Failure, especially autoimmune diseases and the diseases with infection or inflammation, such as Lupus Erythematosus, Rheumatism, diabetes, Cardiovascular disease and all kind of Kidney Diseases. Since so many diseases can bring about Kidney Failure, how can we confirm that we have got Kidney Failure?
From symptoms
Actually, there is no obvious symptom in the early stages of Renal Failure, because many other Kidney Diseases may have the similar symptoms, such as diuresis, oliguria, odynuria, fatigue and so on. However, they can warn you that you should go to check your kidney functions.
In the late stages of Kidney Failure, kidneys lose the most function of removing the metabolic waste and extra fluid in body. The patients will present swelling of feet and legs, high blood pressure, loss of appetite and coma. The damaged structure may cause blood in urine and proteinuria. Acidosis makes shortness of breath. Loss blood in urine and the less production of red blood cells both worsen the conditions of anemia. Disturbance of electrolyte is to bring about bone pain, joint pain and Osteoporosis. In addition, vomit, nausea and diarrhea will occur to the patients with Kidney Failure.
From pathological changes
Some people, who usually take sports and have the body with an unusual compensatory ability, may not show some severe symptoms, even when they are at the late stages of Kidney Failure. Symptoms are behind pathological changes for ever. So the diagnose from those changes is more precise than that from symptoms. The normal tests should include BUN (blood urea nitrogen), creatinine, Ccr (Creatinine clearance rate) and GFR (glomeruli filtration rate). GFR is the most accurate standard to diagnose Kidney Failure. Ccr is secondary to GFR. When GFR is less than 80ml/min, Kidney Failure begins. Comprared with GFR, BUN and creatinine are hysteretic symptoms.
GFR: 50-80ml/min. BUN and creatinine are normal.
GFR: 50-20ml/min. BUN is 7.1 mmol/L and creatinine is 186-442 μmol/L.
GFR: 20-10ml/min. BUN is 17.9-28.6 mmol/L and creatinine is 451-707 μmol/L.
GFR: less than 10ml/min. BUN is more than 28.6 mmol/L and creatinine exceeds 707 μmol/L.
As it is reported, when GFR is more than 50 ml/min, the kidney functions are able to greatly recovered, as long as the effective treatments are adopted. So we should try to test GFR or Ccr, if we feel something with kidneys.

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