Ibuprofen is among the common Nephrotoxic medicines that may possibly induce
kidney failure. The risk of kidney injury is much higher if the medicine is
applied for heavy dosage or over a long course. Kidney damage caused by
Nephrotoxic medicines can sometimes be permanent and irreversible. Thereby, it
is very crucial for us to have a general knowledge of Nephrotoxic medicines and
understand proper ways of preventing kidney involvement. The following are more
details:What are common types of Nephrotoxic medicines?
1. Antibiotics and chemotherapy drugs:
①Commonly seen: amphotericin B, neomycin, cefotaxime, Ⅱ, etc.;
②Less commonly seen: gentamicin, card, kanamycin, streptomycin, tobramycin, amikacin, polymyxin, vancomycin, sulfa drugs, etc.;
③ Occasional seen: penicillin (I, II, III), carbenicillin, chlortetracycline, oxytetracycline, cefotaxime (Ⅳ, Ⅴ and Ⅵ), rifampicin and so on.
2. Non-steroidal anti-inflammatory and analgesic drugs: indomethacin, ibuprofen, aspirin, compound aspirin (APC), phenacetin, security antipyrine aminopyrine, paracetamol and so on.
3.Chemotherapy drugs: cisplatin, methotrexate and mitomycin-C
4.Anti-epilepsy drugs: three pairs of ketones, phenytoin sodium
Other nephrotoxic medicines also include: anesthetics, a variety of vascular contrast agents and so on.
What are symptoms of drug-induced kidney damage?
Patients with drug-induced kidney damage may present various symptoms, such as back pain, changed urine color or urine output, nocturia, swelling in eyelids or lower limbs, anemia, fatigue, etc.
Clinically, however, there are also such cases where patients don’t present any symptom at all.
How to prevent medicine-induced kidney diseases?
1. Take in water before and after consuming the medicines so as to promote excretion of the medicines and alleviate toxicity to the kidneys.
2. Apply medicines under instructions of expert doctors. Never increase medicine dosage or application time on your own will.
3. The elderly, diabetics and kidney disease sufferers should try to avoid Nephrotoxic medicines.
4. For patients with renal insufficiency, medicine dosage should be adjusted based on the specific kidney function.
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Shijiazhuang Kidney Disease Hospital
Shijiazhuang Kidney Disease Hospital is located in Shijiazhuang city, capital of Hebei Province, which is adjacent to the capital of China, Beijing. It was founded in 1986 and his name has become more widely known in recent decades.....Read More
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