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Creatinine is micro molecular substance in blood. It is produced mainly
through muscle metabolism. Normally, creatinine is removed by the kidneys. In
end-stage renal failure, as kidneys are shut off, creatinine will rise
obviously. Besides kidney problem, there are some other contributing causes for
high creatinine levels. We will introduce it one by one for you in the following
passage:
Poorly controlled blood pressure. Hypertensive kidney failure is kidney
failure directly caused by poorly controlled hypertension. Kidneys have the
function of regulating blood pressure by secreting renin. Thereby, in developing
process, almost all kidney disease patients will get high blood pressure. High
blood pressure will make kidneys work harder and impair renal filtration
function, thus making creatinine increase faster.
Poorly controlled Diabetes. Diabetes keeps blood sugar stay at high readings,
severely impairing glomerular filtration system and affecting normal excretion
of creatinine. Fail controlling of blood sugar will make kidney function decline
faster and thus elevating creatinine accordingly.
Combined infections. For patients with various kidney disorders, combined
infections will aggravate renal inflammatory injuries and cause sharp kidney
creatinine elevation. The infection can be a simple cold, pneumonia, enteritis
and urinary infections.
Dehydration: In case the patient drinks insufficient water, the body will be
dehydrated and renal bloodstream will be concentrated. This will make it harder
to excrete creatinine from blood within the kidneys.
Excess protein and meat from the diet. Protein and meat are main sources of
exogenous creatinine. When much protein and meat are supplemented, more
creatinine will be produced, as a result of which serum creatinine will
rise.
Nephrotoxic medicines. The metabolic end product of Nephrotoxic medicines
will be excreted by the kidneys. If a patient with nephritis consumes those
medicines, he will run the risk of accelerating kidney disease progression and
obvious creatinine elevation. It is very necessary for every kidney disease
patient to remember to take special caution with such group of medicines which
includes ibuprofen, aspirin, antipyrine, etc.
Strong muscle activity. Creatinine is metabolized from muscle. Thereby, if
you do a strenuous exercise or severe labor, creatinine is also likely to be
higher. It will be better to do moderate labor, which will help to be better in
energies and strengthen body resistance.
The above introduces causes of high creatinine in end-stage renal failure. As
you can find, there are so many details we need to pay attention to so as to
well control your kidney problem and high creatinine. Dietary adjustments and
daily nursing are basic measures, at the meantime, stem cell treatment and
Chinese medicine to lower creatinine is much more crucial. If you need any
related information, you may consult us for free.
Do you have any question? You can leave a message , Or you Could describe
your symptoms to our expert. Our expert will reply you as soon as possible.
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