2014年1月9日星期四

Edema and kidney disease what kind of relationship do you have

Edema and kidney disease to do?Many people will be found in the case of unknown causes such as face, hands and feet edema, will first consider whether has relationship with kidney, kidney disease.Also often have edema patients to online inquiries, edema is one of the many symptoms of kidney disease, kidney disease cause of renal edema is relatively complex, specific conditions as described below.
1) renin - angiotensin aldosterone system activation to water sodium retention;
(2) the glomerular filtration rate decreased, but the ball - tube unbalance, namely relatively normal renal tubular reabsorption function;
(3) a large number of protein loss caused by the plasma colloid osmotic pressure is reduced, water from intravascular chosen.In a word, water retention of sodium and water ran into tissue clearance is the basis of cause renal edema.
Some chronic kidney damage, although the renal tissue destruction is very heavy, but renal tubular reabsorption of water's ability to reduce more obvious, at this point, even if the glomerular filtration rate is very low, because of the renal tubular reabsorption capacity less than glomerular filtration rate, there is no water sodium retention, so patients can no swelling, or edema is very light.
Nephrotic syndrome patients in some kidney damage is not too heavy, the pathological changes of the kidney is only small lesions, basement membrane damage charge barrier is given priority to, but as a large amount of albumin loss, make patient plasma colloid osmotic pressure drop, water clearance move to the organization.Offshoring due to moisture at the same time, the blood volume to drop, activation of renin angiotensin system, water sodium retention.The edema patients with serious, can appear pleural effusion, ascites or pericardial effusion, like a big "water".But by hormones such as drug therapy, can recover soon.

So, although renal edema is the basis of the water retention of sodium and water move to the clearance, but because of its different emphasis have edema, the degree of edema is not entirely consistent.The degree of this level of different with kidney disease is not necessarily the correlation.That is to say, the degree of edema and there is no direct relationship between the degree of kidney damage.

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