2013年12月2日星期一

Common complications of nephrotic syndrome

1 infection: decreased resistance to infection in patients with nephrotic syndrome, the main reason is due to : Infection : ① urine lost a lot of IgG. ② B factor ( the alternative pathway of complement component ) of immune deficiency leads to bacterial opsonization defects ; ③ When malnutrition, the body's non-specific immune response diminished capacity , resulting in impaired immune function . ④ transferrin and considerable loss of zinc from the urine . Transferrin is necessary for the maintenance of normal lymphocyte function , zinc ion concentration and thymosin synthesis. ⑤ local factors . Pleural effusion, ascites, edema of the skin caused by a high degree of skin breakdown and severe edema dilution factor so that the local humoral defense weakened , are predisposing factors in patients with nephrotic syndrome.

2 , hypercoagulable state and venous thrombosis : the presence of a hypercoagulable state nephrotic syndrome , mainly hypercoagulable state and venous thrombosis : due to changes in blood coagulation factors . Therefore , increased pro- aggregation and procoagulant factors , anticoagulation fall damage and anti-clotting factors and fibrinolytic mechanism is nephrotic syndrome produce a hypercoagulable state reasons. Antibiotics, hormones and diuretics application of aggravating factors of venous thrombosis , clotting protein hormones play a role by , and diuretics are concentrated in the blood , increasing blood viscosity .

3 , acute renal failure : acute renal failure, nephrotic syndrome, the most serious complications.

Complications in patients suffering from nephrotic syndrome do not panic too , should be reasonable and effective treatment. Also, proper exercise, avoid cold, in order to enhance physical fitness, make up their own health

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