High urinary protein

Urinary protein
Under normal circumstances , the body in the urine does not contain protein or contain only trace amounts of protein, but when kidney disease occurs when a protein with the blood circulation flows through the kidneys, since leaving the protein reduced kidney filtration function of the " slipping through the net ." Protein leakage into the urine from the urethra discharged from the formation of proteinuria. Proteinuria kidney filtration function , the worse the higher the note , which is an important indicator of kidney function .
Urine protein level representation
Urine protein level representation
Indicators to measure the level of protein in the urine needs to be done 24 hours urine protein test results appear minus sign - indicates negative , is normal ; out plus sign + indicates positive, plus the more the higher the urinary protein . Specifically expressed as follows : Urine protein <0.1g / L: -; urine protein is 0.1-0.2g / L: ±; proteinuria is 0.2-1.0g / L: +; proteinuria 1.0 ~ 2.0g / L: + +; urine protein is 2.0-4.0g / L: + + +; proteinuria > 4.0g / L: + + + +. g / L expressed per liter (L) in the urine how many grams (g) protein contains .
The reason for the high urinary protein
1,24 -hour urinary protein excretion in normal reference value of 10 to 150 mg. If 150 to 500 mg of microalbuminuria , > 500 mg for clinical proteinuria. Tip microalbuminuria in early diabetic nephropathy , need long-term control of blood glucose , to reverse or delay the incidence of nephropathy and retinopathy development has a certain significance.

2 , urinary albumin excretion rate (uAE) normal reference value < 15 micrograms / min. Early diabetic nephropathy , glomerular basement membrane damage is light, so that only albumin leakage. Early diabetic nephropathy uAE 15 to 200 micrograms / min, clinical diabetic nephropathy > 200 micrograms / min. Experts have reported significant proteinuria in diabetic nephropathy , almost 100% of diabetic retinopathy. When diabetics uAE30 micrograms / min, may be the key moment of microvascular complications of diabetes prevention . After the strict control of blood glucose, urine albumin early diabetic nephropathy can be reversed or partially reversed . At present , the commonly used method of measuring microalbuminuria is radioimmunoassay.