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Toxic nephropathy toxic substances by the kidney caused kidney damage. Often named after renal toxic substances . What are the symptoms of toxic nephropathy performance ? With this question, we have to look at the introduction below .
Proximal tubular dysfunction manifested as Fanconi 's syndrome : Grapes diabetes, urinary amino acids , phosphate urine, sometimes with hypokalemia, toxic heavy metals found in some kidney disease , expired tetracycline toxic nephropathy ; distal renal tubular function diminish the performance of nephrogenic diabetes insipidus : polydipsia , polydipsia , polyuria , found lithium fluoride , demeclocycline caused toxic nephropathy ; renal tubular acidosis : high acidosis , water and electrolyte imbalance ( such as hypokalemia or hyperkalemia , hyponatremia , hypocalcemia , polyuria, polydipsia polydipsia , etc. ) ; renal osteodystrophy : renal rickets or osteomalacia , renal calcification or kidney stones , found in two amphotericin B induced toxic nephropathy .
Light only trace urine protein , red , white blood cells in urine and urinary tube , little or no urine azotemia . In severe cases , there may be a typical manifestation of acute renal failure syndrome , seen aminoglycoside antibiotics , inorganic mercury -induced toxic nephropathy . Fever, rash , swollen lymph nodes , joint pain, blood eosinophilia and other systemic allergic manifestations . Urinary eosinophilia . Also massive proteinuria was nephrotic syndrome , or hematuria . In severe cases of acute renal failure , found a variety of drugs , especially penicillin family , sulfa drugs , anti-tuberculosis drug poisoning .
Exogenous toxins such as penicillamine . Gold salts , venom , bee venom , pollen and other causes of immune glomerular disease, manifested as nephritic syndrome or nephrotic syndrome. The performance is difficult due to glomerular disease and other causes phase difference. Detailed inquiry should be whether the patient has kidney toxicant exposure history , provide the basis for the differential diagnosis , misdiagnosis and missed otherwise .
Toxic nephropathy treatment methods are described below:
1 stop exposure to toxic substances .
2, to promote excretion of toxic substances , the infusion can be applied antidotes be dialysis treatment when necessary. Where small molecular weight, and protein binding less evenly distributed in the body , could be discharged through the blood of dialysis . Where those with high protein binding effect of peritoneal dialysis is good . Plasma replacement therapy should be used with caution .
3 , symptomatic treatment.

4 , take measures according to the type of renal damage . Such as acute drug -induced allergic interstitial nephritis, nephrotic syndrome , the absence of contraindications, available adrenal corticosteroids, immunosuppressive drugs or shock therapy adrenocorticotropic hormone . Renal failure were available peritoneal dialysis or hemodialysis treatment.